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Research shows that postmenopausal women have significantly higher fasting insulin levels and reduced glucose tolerance compared to premenopausal women of similar age and body composition

The medications are typically administered via subcutaneous injection (except for oral semaglutide/Rybelsus), either daily or weekly depending on the formulation

However, these drugs can have side effects and usually require injections

29 The finding that prolonged treatment with IGF-1R inhibitor induced p70S6K1 phosphorylation suggests the importance of p70S6K1 phosphorylation in cell survival when IGF-1R is inhibited (Fig